People involved in Transcrapple

 

Edmund Mach Foundation – FEM

 

Dr. Azeddine Si Ammour, th e Principal Investigator of TranscrApple

Dr. Azeddine Si Ammour, the Principal Investigator of TranscrApple

Education and training

Azeddine Si Ammour studied at University of Geneva, Switzerland. He obtained his PhD in 2002 in plant molecular biology at the University of Fribourg, Switzerland. He worked for several years at the Friedrich Miescher Institute in Basel, Switzerland. He is currently leading a research group in plant functional genomics at the Fondazione Edmund Mach, Italy.

Research interests

Azeddine Si Ammour research interests are towards the understanding of the role and the importance of epigenetics (DNA and histone methylation) and post-transcriptional regulation mechanisms (microRNAs and other small RNAs) in plant development and in response to environmental stresses using genome-wide approaches.

Dr. Mirko Moser

Dr. Mirko Moser

Education and training

Mirko Moser studied biotechnology at the University of Verona, Italy. He obtained his PhD in 2010 at the Johannes Gutenberg University (JGU) in Mainz, Germany.

Research interests

Mirko Moser research interests are the molecular responses and modifications occurring during the interaction between the pathogen Candidatus Phytoplasma mali (‘Ca. P. mali’), the causal agent of apple proliferation, and apple. He has expertise in bioinformatics and molecular biology applied to genome-wide methylation approaches and small RNA studies.

Dr. Elisa Asquini

Dr. Elisa Asquini

Education and training

Elisa Asquini studied biology at the University of Trieste, Italy. She received her PhD in Genetic in April 2006 at the University of Trieste, Italy.

Research interests

Elisa Asquini research interests are epigenetic-related mechanisms in fruit trees.  She has expertise in next generation sequencing (Illumina, 454) applied to RNAs, small RNAs, DNA methylation, and histone methylation.

University of Trento – UNITN

 

Dr. Michela Denti

Prof. Michela Denti

Education and training

Michela Alessandra Denti studied at University of Pisa, Italy. In 1997 she obtained her PhD in Biology from the Scuola Normale Superiore di Pisa, Italy. She worked at the Institute of Molecular Biology and Biotechnology, Heraklion, Greece (1998-2001), and at the Department of Genetics and Molecular Biology, “Sapienza” University of Rome, Italy (2002-2007). Since 2008 she is Principal Investigator of the Laboratory of RNA Biology and Biotechnology at the Centre for Integrative Biology of the University of Trento, Italy, first as Assistant Professor of Molecular Biology (2008 – 2014) and then as Associate Professor of Applied Biology (2014 – present).

Research interests

Michela A. Denti’s research interests range from functional studies of human and plant microRNAs, to microRNAs as biomarkers of cancer, cardiac and neurodegenerative diseases, to the modulation of RNA splicing as a cure for human inherited diseases.

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Dr. Margherita Grasso

Education and training

Margherita Grasso obtained her PhD in Cellular Sciences and Technologies from the Sapienza University of Rome in 2010, followed by a post-doctoral training in the Department of Anatomy, Histology, Forensic and Orthopaedic Medicine at the Sapienza University. In 2011 she started a second post-doc in the Laboratory of RNA Biology and Biotechnology at  the Centre for Integrative Biology of the University of Trento, Italy.

Research interests

Margherta Grasso’s research interests focus on the role of human and plant microRNAs and on microRNAs as cancer, cardiac and neurodegenerative diseases biomarkers.

University of Padova – UNIPD

 

Dr. Alessandro Botton

Dr. Alessandro Botton

Education and training

Alessandro Botton studied at the University of Padova, where he received the PhD in Crop Science – Agrobiotechnology in 2008. He got a permanent position as a researcher in 2011 at the DAFNAE department of the same University.

Research interests

Alessandro’s research is mainly focused on tree crops, especially apple, peach, and grape, with a special interest on fruit development (apple fruitlet abscission in particular) and seed-fruit interactions. Part of his research is traditionally focused also on apple allergens and the search of hypoallergenic genotypes.

Academia.edu | ResearchGate

Giulia Eccher

Dr. Giulia Eccher

Education and training

Giulia Eccher graduated in Food Biotechnology at the University of Padova, Italy, where, in 2011, she obtained her PhD in Crop Science – Agrobiotechnology with a thesis focused on “Setting up of molecular tools for studying abscission in apple (Malus x domestica)”.

Research interests

Giulia’s research interests include the investigation of seed-cortex cross-talk during fruitlet abscission induction, in easy and hard-to-thin apple cultivars (Malus x domestica), the characterization of apple self-thinning genotypes and the study of allergenic potential of fruits. Since November 2014, she has been enrolled in the “TranscrApple” project.

Dr. Francesca Populin

Education and training

Francesca Populin graduated in Molecular Biology in 2012 at the University of Padova, Italy, where, in 2016, she obtained her PhD in Crop Science – Agrobiotechnology with a thesis focused on “A systems biology approach to shed light on apple fruit development ”.

Research interests

Francesca’s research interests include the investigation of seed-cortex cross-talk during ripening, the progression of the ripening syndrome within the fruit and the hormonal-transcriptional-posttranscriptional regulation of apple fruit development. Since the beginning of her PhD, she has been enrolled in the “TranscrApple” project and is now working on the last achievements.

Dr. Matteo Brilli

Education and training

Matteo Brilli graduated in Biology in 2002 at the University of Florence, Italy, where he also obtained a PhD in Genetics in 2007 with a work entitled “Origin and Evolution of Metabolic Pathways”. In 2008 he moved to France, to learn mathematical modelling and then complex network theory at the University of Lyon. In 2013 he moved to the DBGPF at FEM in Trento, where he worked on plant miRNAs and plant pathogens. Since 2016 he is post-doc at the DAFNAE of the University of Padova where he works on omics datasets of apple ad grape.

Research interests

Matteo’s interests span a very wide portion of bioinformatics research, from molecular evolution to big data analysis. He is involved in -omics data analysis and integration, statistics, modeling and inference of biological networks, in prokaryotes, plants and their pathogens, and – recently – cancer.

Publications of TranscrApple results

  1. Baldi, P., Moser, M., Brilli, M., Vrhovsek, U., Pindo, M., Si-Ammour, A. (2017). Fine-tuning of the flavonoid and monolignol pathways during apple early fruit development. Planta  245: 1021-1035 (link: https://link.springer.com/article/10.1007%2Fs00425-017-2660-5)
  2. Giulia Eccher, Maura Begheldo, Andrea Boschetti, Benedetto Ruperti, and Alessandro Botton (2015). Roles of Ethylene Production and Ethylene Receptor Expression in Regulating Apple Fruitlet Abscission. Plant Physiology  169: 125–137 (link: www.plantphysiol.org/cgi/doi/10.1104/pp.15.00358)

Participation to meetings

  1. Francesca Populin, Giulia Eccher, Mirko Moser, Sergi Munné-Bosch, Javier Miret, Annick Moing, Mickaël Maucourt, Sylvain Guyot, Agnes Gacel, Duyen Prodhomme, Elisa Asquini, Azeddine Si-Ammour, Alessandro Botton. “A new strategy to study intra-fruit ripening progression in apple (Malus domestica L. Borkh)”. Poster presented by Alessandro Botton at the 3rd Symposium in Horticulture in Europe held in Chania/Crete (Greece), 17-21 October 2016.
  2. Francesca Populin, Giulia Eccher, Mirko Moser, Sergi Munné-Bosch, Javier Miret, Annick Moing, Mickaël Maucourt, Sylvain Guyot, Agnes Gacel, Duyen Prodhomme, Elisa Asquini, Azeddine Si-Ammour, Alessandro Botton. “Omic approaches to shed light on apple (Malus domestica L. Borkh) fruit development”. Poster presented by Alessandro Botton at the 3rd Symposium in Horticulture in Europe held in Chania/Crete (Greece), 17-21 October 2016
  3. “Ethylene receptors protect the embryo of developing apple fruitlets from the abscission signal (resembling an immune-like mechanism)”. Oral presentation by Alessandro Botton at the 3rd Symposium in Horticulture in Europe held in Chania/Crete (Greece), 17-21 October 2016.
  4. 1st DAFNAE PostGraduate Scientists meeting (Agripolis Campus – Legnaro(PD),  September 22-23, 2016)
  5. III International Symposium on Horticulture in Europe (Chania, Crete, Greece – October 17-21, 2016)
  6. TranscrApple-Final Meeting (Trento – April 5th, 2017)
  7. ARO – Volcani Center (Jerusalem, 5 June 2017) – Seminar (invited) – Apple as a model crop for fruit development: case studies